Anti-ACR Aptamer SELEX Service(Cat#: CTApt-2488)

This is an aptamer development services to screening aptamers binds to the ACR with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ACR
Alternative Names Acrosin; Acrosin Light And Heavy Chain Prepropeptide; Preproacrosin; EC 3.4.21.10; Proacrosin; EC 3.4.21; ACRS; ACR
Gene ID 49
UniProt ID P10323
Target Overview Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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