Anti-ADAMTS18 Aptamer SELEX Service(Cat#: CTApt-1216)
This is an aptamer development services to screening aptamers binds to the ADAMTS18 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ADAMTS18 |
| Alternative Names |
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 18; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 18; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 18; ADAMTS21; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 21; Disintegrin And Metalloprotease-Like Protein; EC 3.4.24.82; EC 3.4.24.- ; ADAM-TS 18; ADAM-TS18; ADAMTS-18; ADAMTS1; MMCAT; KNO2 |
| Gene ID |
170692 |
| UniProt ID |
Q8TE60 |
| Target Overview |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in this gene may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
