Anti-ADAMTS5 Aptamer SELEX Service(Cat#: CTApt-1014)
This is an aptamer development services to screening aptamers binds to the ADAMTS5 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ADAMTS5 |
| Alternative Names |
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 5; Aggrecanase-2; ADAMTS11; ADMP-2; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 5 (Aggrecanase-2) ; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 11; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 5; ADAM-TS 11; ADAM-TS 5; ADAMTS-11; ADAM-TS5; ADAMTS-5; EC 3.4.24.14; EC 3.4.24.82; EC 3.4.24.- ; EC 3.4.24; ADAMTS5; ADMP2 |
| Gene ID |
11096 |
| UniProt ID |
Q9UNA0 |
| Target Overview |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
