Anti-ADAMTSL2 Aptamer SELEX Service(Cat#: CTApt-1290)

This is an aptamer development services to screening aptamers binds to the ADAMTSL2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ADAMTSL2
Alternative Names ADAMTS Like 2; ADAMTS-Like Protein 2; ADAMTSL-2; KIAA0605; ADAMTSL2; GPHYSD1
Gene ID 9719
UniProt ID Q86TH1
Target Overview This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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