This is an aptamer development services to screening aptamers binds to the ADH1B with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADH1B |
| Alternative Names | Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide; All-Trans-Retinol Dehydrogenase [NAD(+)] ADH1B; Alcohol Dehydrogenase Subunit Beta; ADH2; Alcohol Dehydrogenase 2 (Class I), Beta Polypeptide; Epididymis Secretory Protein Li 117; Alcohol Dehydrogenase 1B; Aldehyde Reductase; ADH, Beta Subunit; EC 1.1.1.105; EC 1.1.1.1; HEL-S-117; EC 1.1.1; ADH1B |
| Gene ID | 125 |
| UniProt ID | P00325 |
| Target Overview | The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |