Anti-ADRA1A Aptamer(Cat#: CTApt-1045)

This product is an aptamer which binds to the ADRA1A with an affinity of 1nM~1μM.

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3’ Modification
 
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Summary

Specifications
Target Category Protein
Target ADRA1A
Alternative Names Adrenoceptor Alpha 1A; Adrenergic, Alpha-1A-, Receptor; Alpha-1A Adrenergic Receptor; Alpha-1C Adrenergic Receptor; Alpha-1A Adrenoreceptor; Alpha-1A Adrenoceptor; ADRA1L1; ADRA1C; Alpha-Adrenergic Receptor 1c; G Protein Coupled Receptor; ALPHA1AAR; ADRA1A
Gene ID 148
UniProt ID P35348
Target Overview Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Chemical Modification DNA/RNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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