This is an aptamer development services to screening aptamers binds to the ADRB1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADRB1 |
| Alternative Names | Adrenoceptor Beta 1; Adrenergic, Beta-1-, Receptor; Beta-1 Adrenergic Receptor; Beta-1 Adrenoreceptor; Beta-1 Adrenoceptor; ADRB1R; B1AR; BETA1A; FNSS2; ADRB1; RHR |
| Gene ID | 153 |
| UniProt ID | P08588 |
| Target Overview | The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |