This is an aptamer development services to screening aptamers binds to the ADRM1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADRM1 |
| Alternative Names | Adhesion Regulating Molecule 1; GP110; Proteasome Regulatory Particle Non-ATPase 13; Proteasomal Ubiquitin Receptor ADRM1; 110 KDa Cell Membrane Glycoprotein; Proteasome Ubiquitin Receptor; Rpn13 Homolog; ARM-1; ARM1; Adhesion-Regulating Molecule 1; M(R) 110,000 Surface Antigen; HRpn13; ADRM1; Rpn13; Gp110 |
| Gene ID | 11047 |
| UniProt ID | Q16186 |
| Target Overview | This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |