This is an aptamer development services to screening aptamers binds to the AGPAT2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AGPAT2 |
| Alternative Names | 1-Acylglycerol-3-Phosphate O-Acyltransferase 1; LPAAT-Alpha; 1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (Lysophosphatidic Acid Acyltransferase, Alpha) ; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Lysophosphatidic Acid Acyltransferase Alpha; 1-AGP Acyltransferase 1; EC 2.3.1.51; 1-AGPAT 1; G15; 1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (Acetoacetly Coenzyme A Thiolase) ; Lysophosphatidic Acid Acyltransferase, Alpha; Epididymis Secretory Sperm Binding Protein; Lysophospholipid Acyltransferase; Protein G15; 1-AGPAT1; LPAATA; AGPAT1 |
| Gene ID | 10555 |
| UniProt ID | O15120 |
| Target Overview | This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |