This is an aptamer development services to screening aptamers binds to the AK2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AK2 |
| Alternative Names | Adenylate Kinase 2; Adenylate Kinase 2, Mitochondrial; Adenylate Monophosphate Kinase; ATP-AMP Transphosphorylase 2; ATP:AMP Phosphotransferase; EC 2.7.4.3; ADK2; Testis Secretory Sperm-Binding Protein Li 220n; Adenylate Kinase Isoenzyme 2, Mitochondrial; EC 2.7.4; AK 2; AK2; |
| Gene ID | 204 |
| UniProt ID | P54819 |
| Target Overview | Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2 |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |