Anti-AKR1C2 Aptamer SELEX Service(Cat#: CTApt-1112)
This is an aptamer development services to screening aptamers binds to the AKR1C2 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
AKR1C2 |
| Alternative Names |
Aldo-Keto Reductase Family 1 Member C2; DD2; Dihydrodiol Dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha Hydroxysteroid Dehydrogenase, Type III; Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase; Testicular 17,20-Desmolase Deficiency; Chlordecone Reductase Homolog HAKRD; 3-Alpha-HSD3; DD/BABP; HAKRD; MCDR2; BABP; DD-2; DDH2; DD; Aldo-Keto Reductase Family 1, Member C2 (Dihydrodiol Dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha Hydroxysteroid Dehydrogenase, Type III) ; Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein; Type III 3-Alpha-Hydroxysteroid Dehydrogenase; Type II Dihydrodiol Dehydrogenase; Pseudo-Chlordecone Reductase; Dihydrodiol Dehydrogenase 2; AKR1C-Pseudo; EC 1.1.1.357; EC 1.3.1.20; EC 1.1.1; AKR1C2; SRXY8; HBAB; TDD; |
| Gene ID |
1646 |
| UniProt ID |
P52895 |
| Target Overview |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
