Anti-AKR7A2 aptamer SELEX Service(Cat#: CTApt-1641)

This is an aptamer development services to screening aptamers binds to the AKR7A2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target AKR7A2
Alternative Names Aldo-Keto Reductase Family 7 Member A2; AFAR; Aflatoxin B1 Aldehyde Reductase Member 2; Succinic Semialdehyde Reductase; Aflatoxin Aldehyde Reductase; AFB1 Aldehyde Reductase 1; Aldoketoreductase 7; SSA Reductase; AFB1-AR 1; AFAR1; AKR7; Epididymis Secretory Sperm Binding Protein Li 166mP; Aflatoxin Beta1 Aldehyde Reductase; EC 1.1.1.n11; HEL-S-166mP; AFB1-AR1; AKR7A2
Gene ID 8574
UniProt ID O43488
Target Overview The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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