Anti-Alas1 Aptamer SELEX Service(Cat#: CTApt-2486)

This is an aptamer development services to screening aptamers binds to the Alas1 with an affinity of 1nM~1μM.

Datasheet MSDS COA
Specific Inquiry 
Size
5’ Modification
 
3’ Modification
 
Add To
Online Inquiry

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number

TOP
Summary

Specifications
Target Category Protein
Target Alas1
Alternative Names 5'-Aminolevulinate Synthase 1; 5-Aminolevulinate Synthase, Nonspecific, Mitochondrial; Aminolevulinate, Delta-, Synthase 1; 5-Aminolevulinic Acid Synthase 1; Delta-Aminolevulinate Synthase 1; Delta-ALA Synthase 1; EC 2.3.1.37; ALAS-H; ALAS3; ALASH; Migration-Inducing Protein 4; EC 2.3.1; ALAS1; ALAS; MIG4
Gene ID 211
UniProt ID P13196
Target Overview This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
Online Inquiry
×