Anti-ALDH5A1 Aptamer SELEX Service(Cat#: CTApt-2470)

This is an aptamer development services to screening aptamers binds to the ALDH5A1 with an affinity of 1nM~1μM.

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5’ Modification
 
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Summary

Specifications
Target Category Protein
Target ALDH5A1
Alternative Names Aldehyde Dehydrogenase 5 Family Member A1; SSADH; NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase; Succinate-Semialdehyde Dehydrogenase, Mitochondrial; EC 1.2.1.24; SSDH; Mitochondrial Succinate Semialdehyde Dehydrogenase; Aldehyde Dehydrogenase 5 Family, Member A1; Aldehyde Dehydrogenase Family 5 Member A1; Succinate-Semialdehyde Dehydrogenase; EC 1.2.1; ALDH5A1
Gene ID 7915
UniProt ID P51649
Target Overview This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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