This is an aptamer development services to screening aptamers binds to the ALDOA with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ALDOA |
| Alternative Names | Aldolase, Fructose-Bisphosphate A; Aldolase A, Fructose-Bisphosphate; Fructose-Bisphosphate Aldolase A; Lung Cancer Antigen NY-LU-1; Muscle-Type Aldolase; EC 4.1.2.13; ALDA; Epididymis Secretory Sperm Binding Protein Li 87p; Fructose-1,6-Bisphosphate Triosephosphate-Lyase; HEL-S-87p; GSD12; ALDOA |
| Gene ID | 226 |
| UniProt ID | P04075 |
| Target Overview | This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |