This is an aptamer development services to screening aptamers binds to the ALMS1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ALMS1 |
| Alternative Names | ALMS1 Centrosome And Basal Body Associated Protein; Alstrom Syndrome Protein 1; Alstrom Syndrome 1; KIAA0328; ALMS1; ALSS |
| Gene ID | 7840 |
| UniProt ID | Q8TCU4 |
| Target Overview | This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations in this gene cause Alstrom syndrome. There is a pseudogene for this gene located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |