Anti ALPPL-2 Aptamer(Cat#: CTMM-0223-JL16)

This product is an aptamer which binds to the ALPPL-2 with an affinity of <20 nM.

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Summary

Specifications
Target Category Protein
Target ALPPL-2
Alternative Names GCAP; Germ Cell Alkaline Phosphatase; Alkaline Phosphatase, Placental Like 2; Alkaline Phosphatase, Germ Cell Type; Alkaline Phosphatase Nagao Isozyme
Gene ID 251
UniProt ID P10696
Target Overview ALPPL-2 is ectopically expressed on the cell surface of many pancreatic cancer cell lines and can also be detected in cell secretions, makes this oncofetal protein an attractive target for the serum- and membrane-based diagnosis of pancreatic ductal adenocarcinoma.
Chemical Modification RNA
Length 60-80 nt
Affinity (Kd) <20 nM
Binding Conditions/Buffer 4.5 g/L glucose, 5 mmol/L MgCl₂, 0.1 mg/mL yeast tRNA, and 1 mg/mL bovine serum albumin (BSA) in Dulbecco's PBS
GC Content 38
Molecular Weight 24432.5
Extinction Coefficient 765800
nmoles/OD260 1.091
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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