Anti-AMH Aptamer SELEX Service(Cat#: CTApt-2396)
This is an aptamer development services to screening aptamers binds to the AMH with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
AMH |
| Alternative Names |
Anti-Mullerian Hormone; MIS; Muellerian-Inhibiting Substance; Muellerian-Inhibiting Factor; Anti-Muellerian Hormone; MIF; Mullerian Inhibiting Substance; Mullerian Inhibiting Factor; AMH |
| Gene ID |
268 |
| UniProt ID |
P03971 |
| Target Overview |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
