This is an aptamer development services to screening aptamers binds to the ANXA2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ANXA2 |
| Alternative Names | Annexin A2; Annexin II; Placental Anticoagulant Protein IV; Calpactin I Heavy Chain; Calpactin-1 Heavy Chain; Lipocortin II; Annexin-2; Protein I; ANX2L4; PAP-IV; CAL1H; LPC2D; ANX2; LIP2; P36; Epididymis Secretory Sperm Binding Protein; Epididymis Secretory Protein Li 270; Calpactin I Heavy Polypeptide; Chromobindin 8; Chromobindin-8; HEL-S-270; ANXA2; LPC2 |
| Gene ID | 302 |
| UniProt ID | P07355 |
| Target Overview | This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |