This is an aptamer development services to screening aptamers binds to the AOC1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AOC1 |
| Alternative Names | Amine Oxidase Copper Containing 1; Diamine Oxidase; DAO; Amiloride Binding Protein 1 (Amine Oxidase (Copper-Containing)) ; Amiloride-Sensitive Amine Oxidase [Copper-Containing] ; Amine Oxidase Copper Domain-Containing Protein 1; Amiloride-Binding Protein 1; Kidney Amine Oxidase; Histaminase; ABP1; DAO1; KAO; Amiloride-Sensitive Amine Oxidase; EC 1.4.3.22; AOC1; ABP |
| Gene ID | 26 |
| UniProt ID | P19801 |
| Target Overview | This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |