This is an aptamer development services to screening aptamers binds to the AP4B1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AP4B1 |
| Alternative Names | Adaptor Related Protein Complex 4 Subunit Beta 1; AP-4 Complex Subunit Beta-1; Adaptor Related Protein Complex 4 Beta 1 Subunit; AP-4 Adaptor Complex Subunit Beta; Beta 4 Subunit Of AP-4; Spastic Paraplegia 47; Beta4-Adaptin; BETA-4; Adaptor-Related Protein Complex 4 Subunit Beta-1; Beta Subunit Of AP-4; CPSQ5; SPG47; AP4B1 |
| Gene ID | 10717 |
| UniProt ID | Q9Y6B7 |
| Target Overview | This gene encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |