This is an aptamer development services to screening aptamers binds to the AP5Z1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AP5Z1 |
| Alternative Names | Adaptor Related Protein Complex 5 Subunit Zeta 1; KIAA0415; SPG48; Adaptor Related Protein Complex 5 Zeta 1 Subunit; Adaptor-Related Protein Complex 5 Zeta Subunit; AP-5 Complex Subunit Zeta-1; Zeta5; Zeta; Adaptor-Related Protein Complex 5, Zeta 1 Subunit; Adapter-Related Protein Complex 5 Zeta Subunit; AP5Z1 |
| Gene ID | 9907 |
| UniProt ID | O43299 |
| Target Overview | This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |