Anti-AP5Z1 Aptamer SELEX Service(Cat#: CTApt-1323)

This is an aptamer development services to screening aptamers binds to the AP5Z1 with an affinity of 1nM~1μM.

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Lot Number

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Summary

Specifications
Target Category Protein
Target AP5Z1
Alternative Names Adaptor Related Protein Complex 5 Subunit Zeta 1; KIAA0415; SPG48; Adaptor Related Protein Complex 5 Zeta 1 Subunit; Adaptor-Related Protein Complex 5 Zeta Subunit; AP-5 Complex Subunit Zeta-1; Zeta5; Zeta; Adaptor-Related Protein Complex 5, Zeta 1 Subunit; Adapter-Related Protein Complex 5 Zeta Subunit; AP5Z1
Gene ID 9907
UniProt ID O43299
Target Overview This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862).
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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