Anti-APOBEC3A Aptamer SELEX Service(Cat#: CTApt-2524)
This is an aptamer development services to screening aptamers binds to the APOBEC3A with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
APOBEC3A |
| Alternative Names |
Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3A; Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3A; DNA DC->DU-Editing Enzyme APOBEC-3A; Phorbolin-1; PHRBN; ARP3; A3A; Probable DNA DC->DU-Editing Enzyme APOBEC-3A; Phorbolin I; EC 3.5.4.38; BK150C2.1; APOBEC3A; EC 3.5.4 |
| Gene ID |
200315 |
| UniProt ID |
P31941 |
| Target Overview |
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
