This is an aptamer development services to screening aptamers binds to the APOC1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | APOC1 |
| Alternative Names | Apolipoprotein C1; Apolipoprotein C-I; Apo-CI; ApoC-I; Apo-CIB; ApoC-IB; APOC1 |
| Gene ID | 341 |
| UniProt ID | P02654 |
| Target Overview | This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |