This is an aptamer development services to screening aptamers binds to the APOL1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | APOL1 |
| Alternative Names | Apolipoprotein L1; Apolipoprotein L; APOL; Apolipoprotein L1-B3; Apolipoprotein L 1; Apolipoprotein L-I; APOL-I; ApoL-I; APO-L; FSGS4; APOL1; Apo-L; ApoL |
| Gene ID | 8542 |
| UniProt ID | O14791 |
| Target Overview | This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |