Anti-AREG Aptamer SELEX Service(Cat#: CTApt-2147)

This is an aptamer development services to screening aptamers binds to the AREG with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target AREG
Alternative Names Amphiregulin; Colorectum Cell-Derived Growth Factor; Schwannoma-Derived Growth Factor; Amphiregulin B; AREGB; CRDGF; SDGF; AR; AREG
Gene ID 374
UniProt ID P15514
Target Overview The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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