Anti-ARHGAP11A Aptamer SELEX Service(Cat#: CTApt-2161)

Name: Anti-ARHGAP11A Aptamer SELEX Service
SKU: CTApt-2161
Rating: 5 (1 reviews)

This is an aptamer development services to screening aptamers binds to the ARHGAP11A with an affinity of 1nM~1μM.

Certificate of Analysis Lookup

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Lot Number

Specifications

Target Category	Protein
Target	ARHGAP11A
Alternative Names	Rho GTPase Activating Protein 11A; Rho-Type GTPase-Activating Protein 11A; Rho GTPase-Activating Protein 11A; GAP (1-12) ; KIAA0013; ARHGAP11A
Gene ID	9824
UniProt ID	Q6P4F7
Target Overview	This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein.
Chemical Modification	N/A
Type	DNA
Length	20-80 nt
Affinity (Kd)	1nM~1μM
Binding Conditions/Buffer	PBS; buffer system with Serum; other