This is an aptamer development services to screening aptamers binds to the ARHGAP32 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARHGAP32 |
| Alternative Names | Rho GTPase Activating Protein 32; GC-GAP; GRIT; RICS; RhoGAP Involved In The Beta-Catenin-N-Cadherin And NMDA Receptor Signaling; GAB-Associated Cdc42/Rac GTPase-Activating Protein; Brain-Specific Rho GTPase-Activating Protein; Rho/Cdc42/Rac GTPase-Activating Protein RICS; GTPase Regulator Interacting With TrkA; Rho-Type GTPase-Activating Protein 32; Rho GTPase-Activating Protein 32; P200RhoGAP; KIAA0712; P250GAP; RhoGAP Involved In The -Catenin-N-Cadherin And NMDA Receptor Signaling; Brain-Specific Rho GTP-Ase-Activating Protein; GTPase-Activating Protein For Cdc42 And Rac1; Rac GTPase Activating Protein; GAB-Associated CDC42; ARHGAP32; PX-RICS; MGC1892 |
| Gene ID | 9743 |
| UniProt ID | A7KAX9 |
| Target Overview | RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]). |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |