Anti-ARHGAP8 Aptamer SELEX Service(Cat#: CTApt-1212)

This is an aptamer development services to screening aptamers binds to the ARHGAP8 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ARHGAP8
Alternative Names Rho GTPase Activating Protein 8; Rho-Type GTPase-Activating Protein 8; Rho GTPase-Activating Protein 8; BPGAP1; BNIP-2 And Cdc42GAP Homology Domain-Containing, Proline-Rich And Cdc42GAP-Like Protein Subtype-1; BCH Domain-Containing Cdc42GAP-Like Protein; FLJ20185; ARHGAP8; PP610
Gene ID 23779
UniProt ID P85298
Target Overview This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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