This is an aptamer development services to screening aptamers binds to the ARHGEF2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARHGEF2 |
| Alternative Names | Rho/Rac Guanine Nucleotide Exchange Factor 2; Rho/Rac Guanine Nucleotide Exchange Factor (GEF) 2; GEF-H1; LFP40; Rho Guanine Nucleotide Exchange Factor 2; Proliferating Cell Nucleolar Antigen P40; Guanine Nucleotide Exchange Factor H1; Microtubule-Regulated Rho-GEF; KIAA0651; GEFH1; Lfc; P40; ARHGEF2; NEDMHM; GEF |
| Gene ID | 9181 |
| UniProt ID | Q92974 |
| Target Overview | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |