This is an aptamer development services to screening aptamers binds to the ARID5B with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARID5B |
| Alternative Names | AT-Rich Interaction Domain 5B; MRF2; AT-Rich Interactive Domain-Containing Protein 5B; ARID Domain-Containing Protein 5B; MRF1-Like Protein; DESRT; MRF-23; AT Rich Interactive Domain 5B (MRF1-Like) ; AT-Rich Interactive Domain 5B (MRF1-Like) ; Modulator Recognition Factor 2 (MRF2) ; Modulator Recognition Factor 2; FLJ21150; ARID5B |
| Gene ID | 84159 |
| UniProt ID | Q14865 |
| Target Overview | This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |