This is an aptamer development services to screening aptamers binds to the ARMC10 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARMC10 |
| Alternative Names | Armadillo Repeat Containing 10; SVH; Specific Splicing Variant Involved In Hepatocarcinogenesis; Splicing Variant Involved In Hepatocarcinogenesis Protein; Armadillo Repeat-Containing Protein 10 |
| Gene ID | 83787 |
| UniProt ID | Q8N2F6 |
| Target Overview | This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |