Anti-ASAH2 Aptamer SELEX Service(Cat#: CTApt-2209)

This is an aptamer development services to screening aptamers binds to the ASAH2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ASAH2
Alternative Names N-Acylsphingosine Amidohydrolase 2; Non-Lysosomal Ceramidase; Neutral Ceramidase; N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2; Acylsphingosine Deacylase 2; EC 3.5.1.23; N-CDase; BCDase; LCDase; NCDase; HNAC1; Neutral/Alkaline Ceramidase; Mitochondrial Ceramidase; EC 3.5.1.- ; ASAH2; HCD
Gene ID 56624
UniProt ID Q9NR71
Target Overview Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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