Anti-ASIP Aptamer SELEX Service(Cat#: CTApt-2482)
This is an aptamer development services to screening aptamers binds to the ASIP with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ASIP |
| Alternative Names |
Agouti Signaling Protein; ASP; Agouti-Signaling Protein; Agouti Switch Protein; AGTIL; AGTI; Agouti Signaling Protein, Nonagouti Homolog (Mouse) ; Agouti Signaling Protein, Nonagouti Homolog; Agouti (Mouse)-Signaling Protein; Nonagouti Homolog (Mouse) ; Nonagouti Homolog; SHEP9; AGSW; ASIP |
| Gene ID |
434 |
| UniProt ID |
P42127 |
| Target Overview |
In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
