Anti-ATG4B Aptamer SELEX Service(Cat#: CTApt-2251)

This is an aptamer development services to screening aptamers binds to the ATG4B with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ATG4B
Alternative Names Autophagy Related 4B Cysteine Peptidase; AUTL1; Autophagy-Related Cysteine Endopeptidase 1; Autophagy-Related Protein 4 Homolog B; AUT-Like 1 Cysteine Endopeptidase; Cysteine Protease ATG4B; Autophagin-1; KIAA0943; HAPG4B; APG4B; ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) ; APG4 Autophagy 4 Homolog B (S. Cerevisiae) ; Autophagy Related 4B, Cysteine Peptidase; ATG4 Autophagy Related 4 Homolog B; APG4 Autophagy 4 Homolog B; DKFZp586D1822; EC 3.4.22.- ; EC 3.4.22; ATG4B; Apg4B
Gene ID 23192
UniProt ID Q9Y4P1
Target Overview Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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