This is an aptamer development services to screening aptamers binds to the ATP1A3 with an affinity of 1nM~1μM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Protein |
| Target | ATP1A3 |
| Alternative Names | ATPase Na+/K+ Transporting Subunit Alpha 3; Sodium/Potassium-Transporting ATPase Subunit Alpha-3; Sodium Pump Subunit Alpha-3; Sodium-Potassium ATPase Catalytic Subunit Alpha-3; ATPase, Na+/K+ Transporting, Alpha 3 Polypeptide; Na(+)/K(+) ATPase Alpha(III) Subunit; Na(+)/K(+) ATPase Alpha-3 Subunit; Na+, K+ Activated Adenosine Triphosphatase Alpha Subunit; Sodium/Potassium-Transporting ATPase Alpha-3 Chain; Sodium-Potassium-ATPase, Alpha 3 Polypeptide; Na+/K+ ATPase 3; Dystonia 12; EC 7.2.2.13; EC 3.6.3.9; EC 3.6.3; ATP1A1; ATP1A3; CAPOS; DYT12; AHC2; RDP |
| Gene ID | 478 |
| UniProt ID | P13637 |
| Target Overview | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |