This is an aptamer development services to screening aptamers binds to the ATP1B3 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATP1B3 |
| Alternative Names | ATPase Na+/K+ Transporting Subunit Beta 3; Sodium/Potassium-Transporting ATPase Subunit Beta-3; Sodium-Potassium ATPase Subunit Beta 3 (Non-Catalytic) ; Sodium/Potassium-Dependent ATPase Subunit Beta-3; ATPase, Na+/K+ Transporting, Beta 3 Polypeptide; Sodium Pump Subunit Beta-3; ATPB-3; CD298; Sodium/Potassium-Transporting ATPase Beta-3 Chain; Na, K-ATPase Beta-3 Polypeptide; CD298 Antigen; FLJ29027; ATP1B3 |
| Gene ID | 483 |
| UniProt ID | P54709 |
| Target Overview | The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |