This is an aptamer development services to screening aptamers binds to the ATP4A with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATP4A |
| Alternative Names | ATPase H+/K+ Transporting Subunit Alpha; Proton Pump; ATPase, H+/K+ Exchanging, Alpha Polypeptide; Potassium-Transporting ATPase Alpha Chain 1; ATPase H+/K+ Transporting Alpha Subunit; ATP6A; ATPase, H+/K+ Transporting, Alpha Polypeptide; Epididymis Secretory Sperm Binding Protein; Gastric H(+)/K(+) ATPase Subunit Alph; Gastric H,K-ATPase Catalytic Subunit; Gastric H+/K+ ATPase Alpha Subunit; Gastric Hydrogen-Potassium ATPase; Gastric H,K-ATPase Alpha Subunit; H(+)-K(+)-ATPase Alpha Subunit; EC 3.6.3.10; EC 7.2.2.19; EC 3.6.3; ATP4A |
| Gene ID | 495 |
| UniProt ID | P20648 |
| Target Overview | The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |