This is an aptamer development services to screening aptamers binds to the ATP5PF with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATP5PF |
| Alternative Names | ATP Synthase Peripheral Stalk Subunit F6; ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subunit F6; ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit F6; ATP Synthase-Coupling Factor 6, Mitochondrial; Coupling Factor 6; ATPase Subunit F6; ATP5A; ATP5J; ATPM; CF6; ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit F6; Mitochondrial ATP Synthase, Coupling Factor 6; Mitochondrial ATP Synthase, Subunit F6; Mitochondrial ATPase Coupling Factor 6; Proliferation-Inducing Protein 36; ATP5PF; ATP5; F6 |
| Gene ID | 522 |
| UniProt ID | P18859 |
| Target Overview | Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo complex has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the F6 subunit of the Fo complex. The F6 subunit is required for F1 and Fo interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. This gene has 1 or more pseudogenes. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |