Anti-ATR Aptamer SELEX Service(Cat#: CTApt-2391)

This is an aptamer development services to screening aptamers binds to the ATR with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ATR
Alternative Names ATR Serine/Threonine Kinase; FRP1; Ataxia Telangiectasia And Rad3-Related Protein; Serine/Threonine-Protein Kinase ATR; EC 2.7.11.1; SCKL1; MEC1; SCKL; MEC1, Mitosis Entry Checkpoint 1, Homolog (S. Cerevisiae) ; MEC1, Mitosis Entry Checkpoint 1, Homolog; Ataxia Telangiectasia And Rad3 Related; FRAP-Related Protein-1; FRAP-Related Protein 1; FCTCS; ATR
Gene ID 545
UniProt ID Q13535
Target Overview The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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