This is an aptamer development services to screening aptamers binds to the ATRIP with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATRIP |
| Alternative Names | ATR Interacting Protein; ATM And Rad3-Related-Interacting Protein; ATR-Interacting Protein; FLJ12343; MGC20625; MGC21482; MGC26740; ATRIP; AGS1 |
| Gene ID | 84126 |
| UniProt ID | Q8WXE1 |
| Target Overview | This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |