Anti-AZU1 Aptamer SELEX Service(Cat#: CTApt-2311)
This is an aptamer development services to screening aptamers binds to the AZU1 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
AZU1 |
| Alternative Names |
Azurocidin 1; Heparin-Binding Protein; HBP; Cationic Antimicrobial Protein CAP37; Cationic Antimicrobial Protein 37; Neutrophil Azurocidin; Azurocidin; HUMAZUR; AZAMP; CAP37; NAZC; HHBP; AZU; AZU1 |
| Gene ID |
566 |
| UniProt ID |
P20160 |
| Target Overview |
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
