Anti-B3GNT3 aptamer SELEX Service(Cat#: CTApt-1668)

This is an aptamer development services to screening aptamers binds to the B3GNT3 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target B3GNT3
Alternative Names UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 3; Transmembrane Protein 3; Beta3Gn-T3; Beta-1,3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1,3-N-Acetylglucosaminyltransferase; UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,3-Galactosyltransferase 8; N-Acetyllactosaminide Beta-1,3-N-Acetylglucosaminyltransferase 3; Core 1 Extending Beta-1,3-N-Acetylglucosaminyltransferase; UDP-Gal:Beta-GlcNAc Beta-1,3-Galactosyltransferase 8; Beta-1,3-N-Acetylglucosaminyltransferase BGnT-3; Putative Type II Membrane Protein; Beta-1,3-GalTase 8; Core1-Beta3GlcNAcT; Beta-1,3-Gn-T3; Beta-3-Gx-T8; Beta3GalT8; B3GN-T3; B3GNT-3; HP10328; TMEM3; Beta-1,3-N-Acetylglucosaminyltransferase 3; Beta-1,3-Galactosyltransferase 8; EC 2.4.1.149; EC 2.4.1.146; Beta3Gal-T8; B3GAL-T8; B3Gal-T8; EC 2.4.1; B3GALT8; B3GNT3; BGnT-3
Gene ID 10331
UniProt ID Q9Y2A9
Target Overview This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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