This is an aptamer development services to screening aptamers binds to the B4GALT3 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | B4GALT3 |
| Alternative Names | Beta-1,4-Galactosyltransferase 3; Beta4Gal-T3; UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 3; Beta-N-Acetylglucosaminylglycopeptide Beta-1,4-Galactosyltransferase; UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 3; Neolactotriaosylceramide Beta-1,4-Galactosyltransferase; UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 3; N-Acetyllactosamine Synthase; Beta-1,4-GalTase 3; Nal Synthase; B4Gal-T3; Beta-N-Acetylglucosaminyl-Glycolipid Beta-1,4-Galactosyltransferase 3; Beta-N-Acetylglucosaminyl-Glycolipid Beta-1,4-Galactosyltransferase; Epididymis Secretory Sperm Binding Protein; EC 2.4.1.275; EC 2.4.1.38; EC 2.4.1.90; B4GALT3 |
| Gene ID | 8703 |
| UniProt ID | O60512 |
| Target Overview | This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |