Anti-BAG1 aptamer SELEX Service(Cat#: CTApt-2006)

This is an aptamer development services to screening aptamers binds to the BAG1 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BAG1
Alternative Names BAG Cochaperone 1; BAG Family Molecular Chaperone Regulator 1; BCL2 Associated Athanogene 1; BAG-1; HAP; Glucocortoid Receptor-Associated Protein RAP46; Bcl-2 Associating Athanogene-1 Protein; Receptor-Associated Protein, 46-KD; Bcl-2-Associated Athanogene 1; BCL2 Associated Athanogene; BCL2-Associated Athanogene; Bcl-2-Binding Protein; RAP46; BAG1
Gene ID 573
UniProt ID Q99933
Target Overview The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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