Anti-BAIAP2 aptamer SELEX Service(Cat#: CTApt-1686)
This is an aptamer development services to screening aptamers binds to the BAIAP2 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
BAIAP2 |
| Alternative Names |
BAR/IMD Domain Containing Adaptor Protein 2; Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2; Insulin Receptor Substrate Protein Of 53 KDa; Insulin Receptor Substrate Of 53 KDa; Insulin Receptor Substrate P53/P58; Fas Ligand-Associated Factor 3; BAI1 Associated Protein 2; WASP And MIM Like; IRSp53/58; IRS-58; IRSp53; FLAF3; BAP2; WAML; Insulin Receptor Substrate P5; BAI1-Associated Protein 2; BAI-Associated Protein 2; Protein BAP2; IRSP53; BAIAP2 |
| Gene ID |
10458 |
| UniProt ID |
Q9UQB8 |
| Target Overview |
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
