Anti-BCKDHA aptamer SELEX Service(Cat#: CTApt-1713)
This is an aptamer development services to screening aptamers binds to the BCKDHA with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
BCKDHA |
| Alternative Names |
Branched Chain Keto Acid Dehydrogenase E1 Subunit Alpha; Branched-Chain Alpha-Keto Acid Dehydrogenase E1 Component Alpha Chain; Branched Chain Keto Acid Dehydrogenase E1, Alpha Polypeptide; 2-Oxoisovalerate Dehydrogenase Subunit Alpha, Mitochondrial; 2-Oxoisovalerate Dehydrogenase (Lipoamide) ; BCKDH E1-Alpha; EC 1.2.4.4; BCKDE1A; MSU; Branched Chain Keto Acid Dehydrogenase E1, Alpha Polypeptide (Maple Syrup Urine Disease) ; Branched Chain Keto Acid Dehydrogenase E1 Alpha Protein; Maple Syrup Urine Disease; BCKDHA; MSUD1; OVD1A |
| Gene ID |
593 |
| UniProt ID |
P12694 |
| Target Overview |
The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
