This is an aptamer development services to screening aptamers binds to the BCKDK with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BCKDK |
| Alternative Names | Branched Chain Keto Acid Dehydrogenase Kinase; [3-Methyl-2-Oxobutanoate Dehydrogenase [Lipoamide]] Kinase, Mitochondrial; BCKD-Kinase; EC 2.7.11.4; BCKDHKIN; 3-Methyl-2-Oxobutanoate Dehydrogenase [Lipoamide] Kinase, Mitochondrial; Branched Chain Alpha-Ketoacid Dehydrogenase Kinas; Branched-Chain Alpha-Ketoacid Dehydrogenase Kinase; Branched Chain Ketoacid Dehydrogenase Kinase; EC 2.7.11; BCKDK; BCKDK; BDK |
| Gene ID | 10295 |
| UniProt ID | O14874 |
| Target Overview | The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |