Anti-BFSP2 aptamer SELEX Service(Cat#: CTApt-1740)

This is an aptamer development services to screening aptamers binds to the BFSP2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BFSP2
Alternative Names Beaded Filament Structural Protein 2; Phakinin; LIFL-L; CP47; CP4; Beaded Filament Structural Protein 2, Phakinin; Lens Fiber Cell Beaded Filament Protein CP 47; Lens Fiber Cell Beaded Filament Protein CP 49; Lens Intermediate Filament-Like Light; 49 KDa Cytoskeletal Protein; Bfps2, Cytoskeletal Protein, 49-KD; Beaded Filament Protein CP49; PHAKOSIN; CTRCT12; BFSP2
Gene ID 8419
UniProt ID Q13515
Target Overview More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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