This is an aptamer development services to screening aptamers binds to the BICD1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BICD1 |
| Alternative Names | BICD Cargo Adaptor; Protein Bicaudal D Homolog; Bic-D; Cytoskeleton-Like Bicaudal D Protein Homolog; Bicaudal D (Drosophila) Homolog; Bicaudal D Homolog 1 (Drosophila); Bicaudal D Homolog; BICD1; BICD |
| Gene ID | 636 |
| UniProt ID | Q96G01 |
| Target Overview | This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |